Commentary: The stem cell bridge: Forging a path above cold storage

Reforms in Minnesota: forging the path.

Gaucher Disease: Forging a New Path to the Lysosome

Most lysosomal proteins are tagged with a carbohydrate modification that allows their recognition and transport to the lysosome. In this issue, Reczek et al. (2007) identify a new pathway for protein sorting to the lysosome. They show that beta-glucocerebrosidase-the lysosomal enzyme defective in patients with Gaucher disease-is delivered to the lysosome through its interaction with the transme...

Forging alliances to bridge the research-policy gap.

It is critical that research findings be translated into policy if the research is to be beneficial. Researchers can play a role in bridging the research-policy gap by participating in the drafting of legislation and regulations, by testifying before lawmakers, and by building collaborations with key entities, including non-profit and governmental bodies outside of the health arena. Advocacy is...

Application of the Finite Element Method In Cold Forging Processes

The demand for more efficient manufacturing processes has been increasing in the last few years. The cold forging process is presented as a possible solution, because it allows the production of parts with a good surface finish and with good mechanical properties. Nevertheless, the cold forming sequence design is very empirical and it is based on the designer experience. The computational model...

Microglia as a stem cell

Microglia is considered the only cell population of mesodermal origin, which comprises 10% of the cells in brain parenchyma. Recent neural stem cell (NSC) studies demonstrate that the brain has regenerative potential. NSCs do not give rise to microglial cells, however indicating that NSCs alone cannot complete the regenetion of the brain. Although the role of microglia is not fully understood, ...